MAPT and frontotemporal dementia: Sixty seven different MAPT mutations have been described so far (Moore et al., 2020) causing early onset FTD and Parkinsonian symptoms in many patients due to the involvement of the substantia nigra and functionally related structures, which resulted in the term Frontotemporal Dementia and Parkinsonism linked to chromosome 17 or FTDP-17 (Ghetti et al., 2015).