Among the gene lists of the top 10 most significantly upregulated and downregulated genes interfered by stem cell implantation, NXT2 played pivotal roles in neurodevelopment, whereas Mknk2, Sema6a, and PIR2 are frequently dysregulated molecules in the pathogenesis of multiple cancer types as evidenced by GeneRIF documented by PubMed. This evidence concerns the gene SEMA6A and cancer.