In HepG2 hepatocytes, Listeria infection induced IFNL1 and IFNB1 expression at 24 h p.i., and more significantly at 72 h p.i. (10-fold more for IFNL1 and 4-fold more for IFNB1), but not at 8 h p.i. (Figure 3B). The gene discussed is IFNL1; the disease is listeriosis.