This was confirmed at the protein level, as infection decreased the amount of secreted AHSG and apolipoproteins APOA1, APOE and APOH, in both HepG2 and Huh7 conditioned media, as well as of APOB, APOC3 and SERPINF2 in Huh7 (Supplementary Table S12). This evidence concerns the gene APOE and infection.