Eight of these genes were similarly inhibited by Listeria infection in PMH: they encode (i) the activating enzyme C1S of the C1 complex, (ii) the central component C3, (iii) the membrane-attack proteins C6 and C8A, and (iv) four complement regulators (C1QTNF6, CFH, CFHR2, VTN) (Figure 5). The gene discussed is C6; the disease is listeriosis.