Such as, our laboratory observed that miR-375 can trigger the ferroptosis through targeting SLC7A11, which is essential for miR-375-mediated inhibition on gastric cancer cell stemness (209); Overexpression of miR-148a can inhibit the proliferation of liver cancer cells by targeting TFR1 (32); MiR-184 can inhibit the occurrence and development of liver cancer by regulating the expression of HAMP (210); And overexpression of miR-200b can reduce ferritin levels in vitro and increase the sensitivity of cancer cells to doxorubicin (211). The gene discussed is TFRC; the disease is cancer.