A range of evidence supports these effects: The nuclear localization of β-catenin and YAP/TAZ is found in nearly 80% of hepatoblastoma tissues, and the expression level of both is related to the growth rate of tumor (100); The expression of β-catenin and YAP/TAZ is considered to be a necessary condition for the growth of colorectal cancer and LKB1 inhibits the nuclear translocation of both to inhibit the proliferation of gastric cancer (101). This evidence concerns the gene YAP1 and hepatoblastoma.