YAP1 and neoplasm: A range of evidence supports these effects: The nuclear localization of β-catenin and YAP/TAZ is found in nearly 80% of hepatoblastoma tissues, and the expression level of both is related to the growth rate of tumor (100); The expression of β-catenin and YAP/TAZ is considered to be a necessary condition for the growth of colorectal cancer and LKB1 inhibits the nuclear translocation of both to inhibit the proliferation of gastric cancer (101).