ZAP70 and B-cell chronic lymphocytic leukemia: Several markers have been studied at MBL diagnosis for their capacity to predict progression to CLL, including B cell receptor immunoglobulin (BcR IG) stereotypy, ZAP70 expression, Hb, platelet count and LDH, however none of them was clearly associated with progression to CLL (p≥0.05 in all instances).