HSD17B4 and neoplasm: To further preclude the interaction of VK2 with HSD17B4, the inhibitory rate of tumor growth by VK2 showed that there was no significant difference between control (empty mean/empty + VK2 mean) and HSD17B4 overexpression (HSD17B4 mean/HSD17B4 + VK2 mean) (Figure 5C).