These results might indicate that miR-760 inactivates several cancer-promoting pathways, such as the ROS1/Ras/Raf/MEK/ERK, PI3K/AKT, cAMP, and Notch1/Hes1/PTEN pathways, to realize its oncogenetic role (25, 27, 28, 48). This evidence concerns the gene NOTCH1 and cancer.