We found that circ_0008594 overexpression increased tumor volume, Vimentin expression, and Snail expression, while reduced tumor apoptosis rate, miR-760 expression, and E-cadherin expression in NSCLC xenograft models; moreover, circ_0008594 knockdown exhibited the opposite effect (Figures 7A–E). The gene discussed is SNAI1; the disease is neoplasm.