Transcript levels of IFN-α, IFN-β, and IFN-γ were observed to be downregulated after knockdown of METTL14/YTHDF1 in gastric cancer cell lines, while IFN-α and IFN-β were involved in promoting the accumulation of pDCs in TME and the expression of PD-L1 in CD4+CD25+Tregs [68–70]. This evidence concerns the gene IFNA1 and gastric cancer.