In consistency with the in vitro results from Figure 4, we found that the mRNA (Figure 7C) and protein levels (Figure 7D) of IL-17A, IL-17F, and IL-10 were significant increased by Treg cells from Foxp3Cre-YFPmiR-21f/f mice in all three autoimmune disease models studied. The gene discussed is IL10; the disease is autoimmune disease.