Results shows risk score is negative-correlated with the infiltration of immunocytes in SKCM, especially neutrophils, DC, and CD8+T cells (Figure 3A), indicating these immunocytes could be much less infiltrated in tumors of high risk score group, which is consistent with the previously work revealing the diversity of tumor-infiltrating lymphocytes in melanoma (22). The gene discussed is CD8A; the disease is melanoma.