A significantly increased expression of activation molecules was observed after stimulation with MP_A compared with DMSO in OTD-CoV-2pos and severe COVID-19 patients, while stimulation with MP_B induced CD8 activation in the two OTD groups, even though lower in OTD-CoV-2neg subjects, but not in severe COVID-19 patients (Figures 2A–C). The gene discussed is CD8A; the disease is COVID-19.