CD209 and infection: Nevertheless, it is notable that the latest study demonstrated that dendritic cell-specific ICAM-grabbing non-integrin (DC-SIGN), a mannose-specific C-type lectin mainly expressed in immature DCs within the dermis, lymph nodes, and tonsils (35), renders cell lines (e.g., BHK-21) susceptible to PEDV entry and infection; conversely, blockage of DC-SIGN with mannan inhibited PEDV infection of cells bearing porcine DC-SIGN (36) as evidence that DC-SIGN is a potential receptor or factor involved in PEDV infection.