When BLCA tumors were stratified for high PDGFD expression, high tumor abundance of the ReNK was associated with poor prognosis, and neither the IL2NK nor SPANK phenotypes were associated with patient prognosis, underscoring the strong association between high BLCA tumor expression of PDGFD and poor patient prognosis (Figure 4). The gene discussed is PDGFD; the disease is bladder transitional cell carcinoma.