SPON2 and glomerulosclerosis: Although the pathophysiologic roles of selected mRNAs were not investigated here, previous studies have shown glomerular compartmental mRNAs, comprising NNMT, THBS2, SPON2, COL3A1, and COL1A1, to be involved in podocyte damage (30–32) and glomerulosclerosis (33, 34), and tubulointerstitial compartmental mRNAs, comprising LYZ, C3, FKBP5, and G6PC, to be associated with fibrosis (35–37) and inflammation (38).