Auxological data and 24hour GH profile measured with polyclonal antibodies in 25 with Noonan syndrome (NS) (with PTPN11 mutation (n=16, without n=9) and in 40 with Turner syndrome (TS) (XO in 31 and 9 either mosaicism or isochromosome), compared to children with normal height (n=45). The gene discussed is PTPN11; the disease is Turner syndrome.