Replacing “admission in ICU” with another variable measuring the severity of the infection or possible sequelae (i.e., level of CRP at 1-month follow-up or having a restrictive ventilatory defect at 1-month follow-up), or comorbid conditions associated with more severe infection (i.e., diabetes or high blood pressure) did not change the observed associations or size effects. The gene discussed is CRP; the disease is infection.