In addition, using an in vitro BC models researches demonstrated that mangiferin, a polyphenolic compound from Mangifera indica, and (-)-Epigallocatechin-3-gallate (EGCG), a polyphenolic compound from green tea, inhibit cell migration and invasion through Rac1 signalling (Deng, Tian, and Liang 2018; Y.; Zhang et al., 2009). Here, RAC1 is linked to breast cancer.