Furthermore, most all-grade AEs evidenced by abnormal laboratory testing results were increased ALT (n = 36), proteinuria (n = 34), hyperbilirubinemia (n = 32), hypothyroidism (n = 28), and high cholesterol (n = 28), followed by high triglycerides (n = 27), leukopenia (n = 26), and increased AST (n = 24). This evidence concerns the gene GPT and hypothyroidism.