Treatment with HE reduced the expression levels of inflammation-related proteins (GFAP, CD11b, and TNF-α) and oxidative stress-related proteins (HO1, NQO1, Bax, and ferritin) in the muscles (GC and TA) and spinal cord of hSOD1G93A mice. The gene discussed is GFAP; the disease is hereditary elliptocytosis.