1−, and 1.8-fold (p < 0.05, p < 0.01, and p < 0.05), respectively, in the Tg group compared with in the nTg group; while treatment with the HE in the Tg-HE group significantly reduced the levels of GFAP, CD11b, and TNF-α by 2−, 2. The gene discussed is GFAP; the disease is hereditary elliptocytosis.