In addition to the NF-κB signaling pathway, the TNF signaling pathway, Th17 cell differentiation, the NOD-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation and antigen processing and presentation, the Intestinal immune network for IgA production, Inflammatory bowel disease (IBD), the Toll-like receptor signaling pathway and JaK-STAT signaling pathway were also significantly affected by SBM addition in diets. The gene discussed is NFKB1; the disease is inflammatory bowel disease.