These include the NF-kappaB (NF-κB) signaling pathway, TNF signaling pathway, Intestinal immune network for IgA production, NOD-like receptor signaling pathway, Inflammatory bowel disease (IBD), Th1 and Th2 cell differentiation, Toll-like receptor signaling pathway, Th17 cell differentiation, Jak-STAT signaling pathway, and Antigen processing and presentation. The gene discussed is TNF; the disease is inflammatory bowel disease.