ADAR and Cognitive impairment: We found no change in ADAR1 expression, but there is lower expression of ADAR2 (P = 0.01) and higher expression of ADAR3 in AD cases (P = 0.01), while mild cognitive impairment (MCI) subjects are in the middle and the cognitively non-impaired controls have the highest expression of ADAR2 and lowest expression of ADAR3, a potential RNA editing inhibitor4.