BRCA1 and neoplasm: After the exclusion of 522 BRCA1/2 carriers, stage (ORstage II vs stage I 1.33 [1.03 to 1.72]), tumor size (OR2–5cm vs ≤2cm 1.92 [1.33 to 2.77]), and subtype (ORluminal B [HER2-] vs luminal A 1.46 [1.04 to 2.05]) remained significantly associated with PTV34genes carriership (Table 2).