Schinke et al. showed that PHF19 KD leads to the downregulation of major cancer players such as BCL2, MYC and EGR1 in ARP1 and JJN3 cell lines and to the downregulation of genes within the JAK/STAT pathway in JJN3 cell line only suggesting that PHF19 is somehow involved in the upregulation of these genes [16]. The gene discussed is MYC; the disease is cancer.