When tumours were classified into benign, BOTs, stage I OC, stage II-IV OC, and secondary metastatic cancer, the model showed poor to excellent discrimination between the different subtypes, with AUCs varying between 0.54 and 0.99 when the CA125 level was included in the model and between 0.50 and 0.99 without the CA125 level (Table 4). Here, MUC16 is linked to neoplasm.