In line with the in vitro finding, PKMYT1AR inhibition sensitized tumor cells responding to DDP in vivo by xenograft tumor formation assay, while PKMYT1 forced expression could reverse PKMYT1AR knockdown effect, indicating the specific role of PKMYT1AR/miR-485-5p/PKMYT1 axis during NSCLC progression in vivo (Fig. S6h-m). The gene discussed is PKMYT1; the disease is neoplasm.