The cell proliferation marker Ki67 and cellular apoptosis marker cleaved caspase 3 (CC3) in the xenograft tumors were then examined by immunohistochemical (IHC) staining, and we verified that PKMYT1AR knockdown inhibited tumor cell proliferation but promoted cellular apoptosis in vivo (Fig. 2n-o). The gene discussed is PKMYT1AR; the disease is neoplasm.