In addition, we found that miR-485-5p mimics overexpression decreased PKMYT1 transcript and protein expressions in NSCLC cancerous cell lines, which was validated by luciferase reporter assay, Real-time RT-PCR and immunoblot (Fig. 4h-k and Fig. S4d-e). This evidence concerns the gene PKMYT1 and non-small cell lung carcinoma.