PCOS is associated with pro-inflammatory cytokines and chemokines elevation in plasma, such as interleukin-18 (IL-18) [9], monocyte chemoattractant protein-1 (MCP-1) [10, 11], and chemokine (C-C motif) ligand 3 (CCL3) [10]. This evidence concerns the gene CCL2 and polycystic ovary syndrome.