HMGA2 and gastric cancer: Taken together, these results suggested that the exosomes secreted by miR-107 knockdown sensitive GC cells no longer increased the sensitivity of SGC7901/5-FU cells to chemotherapy drugs 5-FU and CDDP, and reversed drug resistance can be achieved by exosomal transfer of miR-107 possibly through inhibiting HMGA2 expression in SGC-7901/5-FU cells.