Furthermore, a survival prognostic model with 13 genes (FSTL3, CPS1, PTPN21, DEPDC1B, COL9A3, DSG2, LAMB1, STYK1, RBM6, DEPDC1, GTSE1, NAV3, and FKBP5) was constructed for NSCLC through K–M estimator and Cox proportional hazard regression model. This evidence concerns the gene FSTL3 and non-small cell lung carcinoma.