Furthermore, a survival prognostic model with 13 genes (FSTL3, CPS1, PTPN21, DEPDC1B, COL9A3, DSG2, LAMB1, STYK1, RBM6, DEPDC1, GTSE1, NAV3, and FKBP5) was constructed for NSCLC through K–M estimator and Cox proportional hazard regression model. This evidence concerns the gene DEPDC1B and non-small cell lung carcinoma.