NAIP and infectious otitis media: Allam et al. found that mice with all NAIP isoforms deleted (Naip1–6Δ/Δ) were protected from dextran sulfate sodium (DSS)-induced colitis, but had greater tumour burden following treatment with the carcinogen azoxymethane (AOM) alone, and in the AOM/DSS model of colitis-associated cancer.