Likewise, SLC27A4 has been found to be associated with the progression of clear cell renal cell carcinoma and breast cancer,18, 19 SLC27A5 deficiency causes a series of reactions in hepatoma cells, such as increase in polyunsaturated lipids and lipid peroxidation, leading to the proliferation of tumor cells. This evidence concerns the gene SLC27A5 and hepatocellular carcinoma.