Likewise, SLC27A4 has been found to be associated with the progression of clear cell renal cell carcinoma and breast cancer,18, 19 SLC27A5 deficiency causes a series of reactions in hepatoma cells, such as increase in polyunsaturated lipids and lipid peroxidation, leading to the proliferation of tumor cells. Here, SLC27A4 is linked to hepatocellular carcinoma.