In contrast, when WT FBP1 and G260R enzymatically dead mutants were transfected into MIA PaCa‐2 and Capan‐1 cells, overexpression of FBP1 sensitized the pancreatic cancer cells to Olaparib, which was independent of its glucogenic activity (Fig. 1J,K). Here, FBP1 is linked to familial pancreatic carcinoma.