To decipher the regulatory patterns of CCN2 and CCN5 in tissue repair after myocardial infarction, the mRNA levels of CCN2 and CCN5 in the infarcted region and in non-ischemic myocardial tissue were analyzed at three different time points after induction of myocardial infarction in mice (Fig. 1a, b). Here, CCN5 is linked to myocardial infarction.