While the high percentage of non-Asian population and low percentage of Asians in our study may be one of the reasons for the lack of significant association between KCNQ1 rs2237892SNP and T2DM, the second possible reason is that Yu et al. conducted meta-analysis on multiple sites of KCNQ1 gene and further collected and processed on the basis of meta-analysis data; there are cases of attenuated output. This evidence concerns the gene KCNQ1 and type 2 diabetes mellitus.