ERBB4 and diabetic kidney disease: Podocyte-specific lncRNA taurine-upregulated 1 overexpressing DKD mouse models improved glomerular phenotype in terms of albuminuria and histological changes through protecting podocytes from apoptosis and ER stress and alleviating extracellular matrix (ECM) accumulation.11, 12, 13, 14 More recent work suggests that two lncRNAs, Erbb4-IR15 and LRNA9884,16 promote DKD by enhancing kidney fibrosis and inflammation, respectively.