SOX9 and central nervous system cancer: A study of Li et al. proves that downregulation of LINC00174 can inhibit resistance to temozolomide in the glioma cells, the molecular mechanism of which is that LINC00174 can sponge miR-138-5p so as to affect the expression of SOX9 and further improves the resistance to temozolomide and proliferation of glioma cells [14].