MTOR and cancer: NGS analysis (Oncomine®, Thermo Fisher) for the detection of somatic mutations in the coding sequence of 143 cancer-related genes17 was conducted, on this occasion on the DNA extracted from the patients’ metastatic pulmonary lesion, which confirmed the persistence of AKT1 E17K mutation, and an mTOR mutation, mTOR A1459D, annotated to be an activating mTOR mutation.