Furthermore, we uncovered from our latest, extended genetic-imaging UK Biobank study22, further associations of lobule VII with many additional variants principally related to cardiovascular disease and risk factors, including rs56300220, a locus in an exon of LRP8, rs2199936, in an exon of ABCG2, as well as two introns in MFHAS1. The gene discussed is LRP8; the disease is cardiovascular disorder.