NFKB1 and cancer: However, the expression of inflammation and cancer-progressing genes33,34,39–41 (e.g., A20, JUNB, and LTB) were also observed when IκBα was present, indicating that IκBα enables the full induction of not only NFκB-regulated genes that promote apoptosis, but also NFκB-regulated genes that promote inflammation and cancer progression.