Cardiovascular disorders have also been reported sporadically in patients with the UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) myopathy and SLC7A4 deficiency, and the cardiac phenotype has also been observed in the N-acetylneuraminate-pyruvate lyase gene (npl) morphant zebrafish34. The gene discussed is NPL; the disease is myopathy.