SYK and Hepatic fibrosis: First of all, the superposition of the inflammation cascade in the liver fibrosis model injected with CCL4 for a long period of time leads to a chaotic map of inflammation induction and regression, which to some extent affects our judgment on the targeting of syk, although we determined our treatment is mainly CD206 + MoMF is targeted, but it does not rule out that a small part of kupffer cells that regenerate after death are affected.