Our findings illustrate that CAFs-exo upregulated the expression of MMP9 and ICAM-1, overexpression of TCEAL7 can rescue the effects of CAFs-exo on MMP9 and ICAM-1, indicating CAF exosomes have a promoting effect on breast cancer cell invasion and metastasis, while TCEAL7 has an inhibitory effect on breast cancer cell invasion and metastasis. The gene discussed is TCEAL7; the disease is breast cancer.