Our findings illustrate that CAFs-exo upregulated the expression of MMP9 and ICAM-1, overexpression of TCEAL7 can rescue the effects of CAFs-exo on MMP9 and ICAM-1, indicating CAF exosomes have a promoting effect on breast cancer cell invasion and metastasis, while TCEAL7 has an inhibitory effect on breast cancer cell invasion and metastasis. This evidence concerns the gene ICAM1 and breast carcinoma.