CAP1 and viral infectious disease: The bait NAs were chosen to resemble NAs commonly found during viral infections and that are known to activate or be targeted by the innate immune system: synthetic double-stranded (ds)RNAs (poly(I:C) and poly(A:U)), 5′ modified in vitro transcribed dsRNA (dsRNA-PPP and dsRNA-CAP0) and 5′ modified in vitro transcribed single-stranded (ss)RNAs (ssRNA-PPP, ssRNA-CAP, ssRNA-CAP0, and ssRNA-CAP1) (Supplementary Data 1)20–38.