In addition, ECM components produced by CAFs and CAFs-derived cytokines including C-C motif chemokine ligand 5 (CCL5), IL6, and C-X-C motif chemokine ligand 10 (CXCL10) were found to regulate cancer cell metabolism by impacting on different signaling pathways [84–86]. Here, CXCL10 is linked to cancer.