We also found that BUB1 was positively related to STAT3 based on TCGA data in the online GEPIA database (R = 0.21; P < 0.05; Fig. 2D), which further supports the hypothesis that BUB1 might regulate the progression and prognosis of bladder cancer by mediating the STAT3 signaling pathway. This evidence concerns the gene BUB1 and urinary bladder carcinoma.