The locus 19q13.32 (TOMM40/APOE/APOC1) is a widely replicated locus for lipid traits including apolipoproteins levels,68 LDL-C,33,37–40,42,43,69–77 HDL-C,33,42–44,56,72,74,76,78 total cholesterol,33,42,43,56,72,74–76,78 triglycerides42 as well as for CAD.35,47,63 Table S17 shows the 14 cIMT variants which were also significantly associated with CAD from the meta-analysis of UK Biobank and CARDIoGRAMplusC4D.35 Here, APOE is linked to coronary artery disorder.