Nevertheless, several of them, SELL, GZMB, and CCR7 (at 3 dpi), and HAVCR2 (TIM-3), TNFRSF9 (CD137), and GPR18 (at 6 dpi) were promptly upregulated for the virulent Lena strain, probably associated with the marked clinical signs, the earlier and stronger peak of replication, and severe pneumonia. Here, GPR18 is linked to pneumonia.