Human milk has multiple constituents that are known to protect infants from infection and disease, including secretory IgA (sIgA) antibodies, its own microbiota, human-milk oligosaccharides, and other antimicrobial factors (e.g., lactoferrin, ɑ-lactalbumin, B-defensins), glycoproteins, and extracellular vesicles (43–45). The gene discussed is LTF; the disease is infection.