ENO1 and hematocrit: If any of these serum Ab recognize epitopes of the corresponding thyroid autoantigen that fall in regions sharing homology with any of the known HT/SREAT autoantigens (alpha-enolase, AKRIA, DDAHI) and/or any of the CNS-expressed proteins we report here, once it/they has/have been proved as autoantigens associated with HT/SREAT, then HT or GD patients can be sorted out in terms of risk for HT/SREAT.