Of the 3 MMRD gliomas with low mutation numbers (5 SNPs), GBM IDH-wt (Case #7) had many copy number aberrations, but the remaining DMG (Case #7) and PXA (Case #13) did not have many copy number aberrations, eventhough they had MMRD (Supplementary Table 3). This evidence concerns the gene IDH1 and glioma.